3. Biomaterials for bone tissue-engineering Essay

3. Biomaterials for bone tissue-engineering - Essay Example Osseointegration means the ability to integrate into surrounding bones. The ideal condition is that the tissue should be reabsorbed and may be even replaced by the body’s own regenerated biological tissues. Bioactive inorganic materials like tricalcium phosphate, HA, bioactive glasses have a large capacity to be re-absorbed. This is definitely one of the positive points of inorganic materials. But the main problem is their brittle nature. This brittle nature means that the fracture toughness of the bones cannot b matched by these materials and thus is not ideal for picking heavy loads. Polymers such as collagen and hyaluronic acid are polymers which are interesting options for the use (Seeherman H, 2008).However they have weak mechanical properties and provide a possible risk of diseases if there is poor handling. Hydrogels are the kind of polymers which are creating great buzz about their use. They have many advantages including the one that chemical biofunctionalisation and cell encapsulation and delivery are very straightforward. In order for the biomaterial to be like a real bone the toughness of a polymer needs to be combined with the compressive strength of an inorganic material (Hollinger, 2004). This improves their mechanical properties and degradation profiles. Once the adequate biodegradable polymer has been selected the next step is to find a suitable processing technique. The processing methodology must not adversely affect the biocompatibility or the chemical properties of the chosen materials. Through the years a variety of processing techniques have been developed. Some of them will be discussed here by us. Solvent casting /Particulate Leaching – This method consists of dispersing calibrated materials such as sodium chloride or organic materials like saccharine particles in a polymer solution. The dispersion is processed after this either by casting or by using the method of freeze drying which results in

Morocco Country Risk Assessment Essay Example | Topics and Well Written Essays - 1000 words

Morocco Country Risk Assessment - Essay Example Having been inhabited back in the Paleolithic times, most of the citizens are either Arabs or Berbers with the latter ethnic group forming the bulk of the population. Other ethnic groups that form part of the population include Haratin and Gnaoua. Additionally, the country is inhibited by more that 100,000 foreigners including Spanish and French who have invested in various sectors thus improving the country economic performance. Culturally, Morocco is known for being an ethnically diverse nation based on its hosting various foreigners who come from the East, South and other regions. Some of the key visitors who have contributed to the cultural growth of the country include Carthaginians, Arabs, Phoenicians, Romans, Andalusians, Jews and Vandals among others. Due to the interaction of the various groups in the country, Moroccan literature has continued to experience an expansive growth. For example, western and Middle East literary models have enhanced the growth of poetry and tradit ional Moroccan genres (Yahya 49). Similarly, the country rich cultural values have attracted expatriates academic and social writers such as Paul Bowles and Pierre Loti among others. Infrastructure One of the major factors that make Morocco a good country for investors is the highly developed infrastructure system as compared to other African countries. For instance, the country is served by more that 35, 946 miles and 18,800 miles of primary roads and secondary roads respectively. As a result, the cost of transporting raw materials and finished products within the country is low thus resulting to high profits by the local and foreign investors. Additionally, the government has continued to issues large number of licenses to... This paper stresses that a vital factor that makes Morocco a viable country for investors is the electrical power development. National Office of Electricity is the main government-owned firm that is responsible for providing electricity power in the country. Even though the country has significant oil reserves, most of the power was earlier generated from imported fuels from Saudi Arabia. This report makes a conclusion that Morocco is ruled under the constitutional monarchy with the prime minister holding major powers while the king hold few executive powers including dissolving the parliament. Two major chambers in Morocco parliament are the assembly of councilors and the assembly of representatives. To ensure justice in the country judicial system, the country constitution provides for an independent judiciary. In this way, politicians do not have much impact on the country court system thus reducing the level of corruption in the country. One of the remarkable political initiatives that occurred in 2011 was the drafting of new constitution that brought about major reforms in the country political system. For example, the king was given power to appoint a prime minister from the party with the majority seats in parliament. Similarly, the prime minister was given power to appoint high level diplomats and chief executive officers of the government owned organizations. It is worth noting that the constitutional also gave power to all citizens by ensuring freedom of creation, ideas, thought among others.

ABC Orange Juice Essay Example | Topics and Well Written Essays - 250 words - 1

ABC Orange Juice - Essay Example They ought to understand their aim of advertising, the target, media and competitors. ABC must actively involve the public, customers or not, in any activity which presents a forum for the customers to make comments about their Juice. This helps develop referrals and positive word of mouth from satisfied customers. Stake holders are very vital for the overall performance and success of the business hence they must be involved too. The public relations team must make available this forum by participating in community activities and sponsorships, producing annual reports, brochures and newsletters. In addition, they may also initiate educational programs to enlighten the public on the need to use their juice instead of others. ABC Orange juice in a move to market their product will employ sales promotion techniques such as sales force promotion, trade promotions, business promotions and consumer promotions. They will give appropriate commissions to their sales agents to motivate them. They may also involve them in sales competition with prizes or awards. In business promotion, they need to organise seminars and workshops and trade show displays. They can as well appease their customers by offering on-pack offers, bonuses and loyalty

The Construct Surrounding Earnings Management Research Paper

The Construct Surrounding Earnings Management - Research Paper Example There are two types of intentional misstatements which are significant in the auditor’s assessment of fraud. These are (1) misstatements that arise from fraudulent financial reporting, and (2) misstatements that arise from the misappropriation of assets. Classified under the first type are those intentionally false and misleading statements or the omissions of amounts or disclosures that should be included in financial statements. Included in the second type are acts that constitute theft of an entity’s assets which are attended with misrepresentation thereof in the financial statements. Misappropriation of assets includes such acts as ‘embezzling receipts, stealing assets, or causing an entity to pay for goods or services not received’.There are situations where a fine line may be drawn between earnings management motivated by a desire to mislead or misrepresent, and a legitimate resort to management prerogative is being made. As noted by the official docu ment from the Public Oversight Board (2002), in par. 3.10:â€Å"Many of the factors cited in SAS No. 82 are subjective and difficult to assess, and risk factors may exist in circumstances where fraud does not exist. Even when risk factors are present and the auditor’s response to them is not definitively prescribed by the standard, SAS No. 82 states that ‘the auditor’s judgment may be that audit procedures otherwise planned are sufficient to respond to the risk factors.†.... As noted by the official document from the Public Oversight Board (2002), in par. 3.10: â€Å"Many of the factors cited in SAS No. 82 are subjective and difficult to assess, and risk factors may exist in circumstances where fraud does not exist. Even when risk factors are present and the auditor’s response to them is not definitively prescribed by the standard, SAS No. 82 states that ‘the auditor’s judgment may be that audit procedures otherwise planned are sufficient to respond to the risk factors.† (p. 76). Thus it is important to assess whether the actions that may be attribute to earnings management are actually motivated by the intent to defraud, mislead or misrepresent. In this matter, the auditor is admonished to exercise professional skepticism as the general standard of due professional care. This means ‘having an attitude that includes a questioning mind and a critical assessment of audit evidence’ (par. 3.8, p. 76). The standard requ ires the auditor to take a position that does not assume the management is dishonest on the one extreme, nor that the management possesses unquestioned honesty on the other, but that the auditor should be persuaded by the evidence unearthed by his or her investigation (Public Oversight Board, 2002).. The Motivation behind Earnings Management The foregoing definition notwithstanding, some authors defend some of the actions of corporate management by distinguishing between ‘good earnings management’ from ‘bad earnings management’ (Farag & Elias, 2012, p. 187). Ostensibly, good earnings management implies legitimate business decisions, which effectively stabilized the financial performance of the company, while bad earnings management involves violations of the GAAP. Good

Approaces in normative ethics Essay Example for Free

Approaces in normative ethics Essay There are three major approaces in normative ethics including virtue ethics, deontological ethics, and utilitarianism. This paper is going to compare the similarities and differences between virtue theory, utilitarianism, and deontological ethics. It will include a description of the differences in how each theory addresses ethics and morality and it will also discuss an experience to explain the relationship between virtue, values, and moral concepts as they relate to one of the three theories. Differences In How These Theories Address Ethics and Morality Virtue ethics, deontological ethics, and utilitarianism are the three major approaches in normative ethics. Virtue ethics emphasizes the virtues, or moral character, while deontology emphasizes duties or rules, and utilitarianism emphasizes the consequences of actions. Virtue ethics is also called agent-based or character ethics. According to Boylan (2009), when using the virtue ethics approach, one should take the viewpoint that in living their life they should try to cultivate excellence in all that they do. It encourages people to develop their character as the basis for the good life. Utilitarianism is a form of consequentialism, meaning that the moral worth of an action is determined by its outcome. Utilitarianism suggests that an action is morally right when that action produces more total utility for the group than any other alternative (Boylan, 2009). Deontological ethics judges the morality of an action based on the actions adherence to a rule or rules. This form of ethics uses rules and duties to determine what is â€Å"right†. Deontological ethics is opposed to consequentialism. Deontology maintains the wrongness of actions resides in the kind of action that it is, rather than the consequences it brings about. A deontologist, for example, would find the act of killing an innocent man wrong simply because it is the killing of an innocent man. A consequentialist might find this action wrong because it deprives someone of future happiness and causes grief to a family. Virtues, Values, and Moral Concepts For individuals who follow the deontology theory, they must apply obligations and rules to their personal conduct. An individuals obligation is to make sure they pay their bills. This helps them to support their family, which is an obligation to people who accept this kind of lifestyle. Some individuals accept not to follow this path in life. A person could easily look at an electric bill and throw it off to the side, and instead, take the money and gamble it away. This would not be the case for a deontologist. A deontologist follows their obligations. A person who follows the theory of a deontology also has to think about virtue, value, and moral concepts. There really is no way to separate the three, as they all play into the same hand. When confronted with a moral or ethical dilemma, virtue, value, and moral concepts all play a part in an individuals thinking process. Conclusion There are three major approaches in normative ethics: virtue ethics, utilitarianism, and deontology. All of these theories are used by mankind to determine what is â€Å"right† and what is â€Å"wrong†. Whatever theory an individual accepts to use as their guide, it is important to accept one of these theories in an effort to help ourselves and mankind. References Boylan, M. (2009). Basic ethics (2nd ed.). Upper Saddle River, NJ: Prentice Hall. Hursthouse, R. (2010). Virtue Ethics. The Stanford Encyclopedia of Philosophy (Winter 2010 Edition). Retrieved from http://plato.stanford.edu/cgi-bin/encyclopedia/archinfo.cgi?entry=ethics-virtue

Integumentary System Disorders

Integumentary System Disorders This report discusses about disorders of integumentary system their pathophysiology, sign and symptoms and their medications. Skin is an organ of integumentary system which protects our body from several types of harms like it work as an umbrella for deeper tissues and it eliminates the wastes from body in the form of sweat and it also maintain the temperature of human body. Skin Human body is covered by a layer of skin, which has two main layers and it is accounts approximately 10 to 15% weight of human body. Skin works as a barrier against ultra violet radiations. Skin has two layers, epidermis is out and dermis is inner layer of skin. Hypodermis layer is made by adipose tissue thats why it is not consider as a major layer. Epidermis It is surface of the skin which is rest on the fatty subcutaneous layer. Epidermis has four layers stratum germinativum, stratum spinosum, stratum granulosam, and stratum corneum. It doesnt contain blood vessels and totally depends upon dermis for the transportation of nutrients and elimination of the waste. Dermis Dermis is inner layer of human body and it also has two layers papillary layer and reticular layer. Dermis is more complicated in structure. Reticular consists thick layer and thick combinative tissues with large blood vessels and papillary layer is made up of thin layer and loose connective tissues with capillaries and elastic fibres. Hypodermis It is the thickest and innermost layer of the skin which release chitinous cuticle. It is fat storage layer. Hypodermis works as an energy holding part of human body. It converts fat in energy and put back in the circulation and sent it to needy areas via venous route. Functions of skin Skin is the biggest organ of human body in surface and mass. Skin has three main functions. Sensation, regulation and protection. Sensation is a major function of skin, by this function we feels heat, cold, touch and pain. Regulation- skin maintains the body temperature via sweat and hair and also balances the body fluid via sweat. Skin works as a barrier for our body, it prevent our body form ultra violet rays and many bacterial infections. Disorders Stasis dermatitis It is a type of dermatitis. Stasis dermatitis is a common skin inflammatory disease occurs on below the ankles. It occurs due to poor blood circulation and in complicated cases it can progress in ulcers. Usually it happens when blood is collects in the veins of lower legs and that bloods increases pressure in the veins which harms the capillaries. This damage of capillaries forces the proteins to leak in the tissues. This leakage causes legs to swell. Thats why the people suffering with this disease usually have swollen legs, open sores itchy skin. Sign and symptoms A person who is suffering from this disease has some symptoms like in first stage the skin of legs become thin. Skin blemish Prickle Scaling Ulcers, sores Leg swelling Calf pain Heaviness in legs Medications Drug Brand name Dosage Side effects Triamcinolone Triderm, Kenalog 3-4 times daily on effected area. Irritation, hypertrichosis, itching. Pimecrolimus Elidel Apply thin layer q12hr on affected area. Burning sensation, headache. Tacrolimus ointment Protopic Apply thin layer q12hr on affected area. Skin erythema, headache, burning sensation. Cutaneous candidiasis Candidiasis is a skin disorder which occurs by the excessive growth of candida fungus on skin. The person who is suffering from this disease has red rash and itchy skin. In early stages it can be prevent by antifungal creams and powders. It may cause by hot weather, rare undergarment changes, poor hygiene and obesity. Usually candida fungi are developed in warm and moist areas like fold of skin, armpits, under breast and between the fingers. It can also effects nails. Sign and symptoms Ring worms Rash on body Crack on the fold areas Rash on genitals Patches of red and purple colour on hips and under breast. Medications Drug Brand name Dosage Side effects Miconazole fungoid tincture, cavilon antifungal cream Apply twice in a day without rubbing. Irritation, hypersensitivity. Terbinafine, topical Lamisil Apply on folding areas for up to 4 weeks. Allergic reactions, redness and itch. Ketoconazole, topical Nizoral topical, extina Apply once daily for 2-3 weeks Burning sensation, irritation, and allergic reaction.

Reintroduction of the Lynx Does More Harm Than Good :: Argumentative Persuasive Topics

Reintroduction of the Lynx Does More Harm Than Good   Ã‚  Ã‚  Ã‚  Ã‚  There I was, standing face to face with the bobtailed lynx. It was looking right at me and licking its chops with delight. It seemed as if the beast was thinking "Lunch" on this cold, gray December day, but I wasn't worried about being attacked. The reason for this was the fact that this was a domestic lynx that just happened to be on the other side of a stout metal cage, so there was no chance of the lynx getting a hold of me.   Ã‚  Ã‚  Ã‚  Ã‚  At one time, the lynx lived all the way along the Continental Divide clear up into Canada. Now, after being gone from Colorado for 25 years, the animal has been reintroduced into the lower tip of the lynx's historic habitat, the San Juan Mountains (Rogers). So far, out of 33 lynx that are being tracked, all of them are roaming in 276 square kilometers of the southwestern portion of Colorado that runs from the New Mexico border up to the I-70 corridor and from Monarch Pass over to Taylor Mesa (Shenk). In an attempt to find out how the animals, which look like bobcats with black tufts on their ears and huge paws, act in nature, scientists are tracking them with radio collars and airplanes (Lloyd).   Ã‚  Ã‚  Ã‚  Ã‚  Now, just a couple of years later, the Colorado Division of Wildlife is planning to release over 180 more lynx into the Colorado wilderness within the next five years. However, out of nearly 100 Canadian Lynx that have already been released so far, about half of them have died and none of them have reproduced. With the type of results that the process has received so far, the agencies involved in the reintroduction process should stop reintroducing the lynx into Colorado. Instead, they should try to find a way different way that will get results that save the species. The government agencies that are involved in reintroducing the lynx argue that it should be done in order to save an endangered species. In this argument they bring out three strong points for trying to save the lynx: every animal should have the opportunity to exist, many people feel happy when they see the animals they share the land with and all living things are part of a complex ecosystem ("Wild life Commission . . ."). However, they aren't sure how to reintroduce the lynx so that they don't all die.